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Treating anti sperm antibodies







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Antisperm Antibodies or immunity to sperm, whether in the male or female, is not an absolute cause of infertility. Sperm antibodies reduce fertility, but do not invariably prevent conception. Rather, the effects are graduated; i.e., the larger the immunologic response, the less likely it is that a pregnancy will occur.

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The immune system thereby develops anti sperm antibodies and attacks sperm entering the system during sexual intercourse. Antisperm antibodies tend to latch on to healthy sperm and affect them. They lower sperm motility which makes it difficult for the sperm to pass through cervical mucus during intercourse.

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Anti-sperm antibodies (ASA) form a class of glycoproteins commonly found in infertile men. This class of antibody causes an impairment of the spermatozoon's ability to cross cervical mucus and interact with the oocyte.

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Sperm antibodies in cervical mucus cause the heads of the sperm to stick to the cervical mucus. To treat sperm antibodies in the mucus you'll need to use condoms for months while the woman's immune system is addressed with diet, nutritional supplements, herbs and other complementary medicine treatments as required.

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Anti-sperm antibodies can occur both in men and women. They are frequently seen in men after vasectomy, testicular injury, or infection. The cause of anti-sperm antibodies in the woman is unknown.


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Like the name says, antisperm antibodies fight sperm. It happens when the immune system mistakenly targets sperm in a man's semen as an invader and damages or kills it. Antisperm antibodies aren. The anti-YWK-II antibody can agglutinate human sperm, interfere with sperm-egg interaction, and arrest the growth and development of zygotes or embryos [1] BE protein.

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Anti-sperm agglutinating antibodies work by making sperm cells clump together to slow it up, while anti-sperm immobilizing antibodies directly prevent the sperm from moving. The presence of which antibody depends on the person, but both of them can contribute to problems getting an egg fertilized. Sperm-counts became normal in 10 men and 4 of their wives became pregnant. 14 men with normal sperm-counts received the same treatment: antibody titres fell slightly and 3 of their wives became pregnant. 18 other men with normal sperm-counts were given one or more courses of methylprednisolone 96 mg/day for 7 days.

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Antisperm antibodies are immune-reactive particles produced by the body as a response against the proteins contained in sperm. The male may produce antibodies to his own sperm (rare) as a result of contact between blood cells and sperm, as through testicular trauma, varicocele, vasectomy, intercourse, or sometimes for unknown reasons. Antisperm antibody can be produced by either partner. It is defined as a certain class of protein attaches themselves to the sperm, causing other cells in the immune system to attack them, leading to low quality sperm in men and effecting the ability of sperm to fertilize the egg in women.

Description:Laboratories (IBL) Sperm Antibody Enzyme Immunoassay Kit. The test is based on a non-competitive ELISA technique. The strips were incubated with patient diluted sera (), and after washing steps, were incubated again with peroxidase conjugated anti-human-Ig (IgA, IgG and IgM). Following the final wash and. Twenty infertile couples with antisperm antibodies in the male or in the female partner were scheduled for treatment. In 15 couples the male and in 5 couples the female partner was the antisperm antibody carrier. In all the couples the result of the in vivo and in vitro sperm-penetration test was negative or poor. The results are given in terms of the number of motile sperm affected by antisperm antibodies surface antibodies may affect both movement of the sperm and the ability of the sperm to bind to the oocyte results are clinically significant and positive if more than 50% of sperm are affected by either class of antibody.
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